國際文獻
食用蘋果萃取物可促進毛髮生長(可發現第0到第60天的毛髮數量增加)
(Tenore,. et al., 2018.)
This includes:
- 蘋果多酚攝取後之外觀相關觀察指標變化
- 60天臨床追蹤分析
- 支持其於植物多酚與營養科學研究領域之學術討論價值
Note: 本內容僅為研究應用方向整理，非效果或結果宣稱
適用族群
適用劑型
膠囊
錠劑
粉包
相關資訊
常見問答
主要成分為來自義大利原生 Annurca 蘋果的萃取物，富含原花青素 (OPC) 與多種植物多酚
PGI 是地理標誌保護認證，確保蘋果來自正統原產地，並保障其品質的一致性與來源可靠性
採用傳統的「日曬熟化工藝」，讓蘋果在自然環境下成熟，進而提升多酚與 OPC 的含量表現
人體研究主要針對攝取後 60 天的臨床追蹤分析，觀察其外觀相關指標的變化
適合注重形象的上班族、注重外表的女性、有髮量困擾的男女，以及關心保養的銀髮族
AnnurtriComplex®可以應用於粉末、膠囊、錠劑、飲品以及保養品中
AnnurtriComplex® 來自 PGI 認證產區，且特別強調高濃度的多酚與 OPC 成分組成，並非一般僅提供風味或基礎營養的蘋果粉
是的，該原料已通過 FSSC 22000、Halal (清真認證) 與 Kosher (猶太認證) 等國際認證
是的，AnnurtriComplex®具有成分分析與多酚數據，並可提供規格書 (Specification) 說明
推薦搭配黃金小米萃取物 (Millet®)，兩者結合可提供更全面的外觀營養支持
參考文獻
Tenore, G. C., Caruso, D., Buonomo, G., D'Avino, M., Santamaria, R., Irace, C., ... & Novellino, E. (2018). Annurca apple nutraceutical formulation enhances keratin expression in a human model of skin and promotes hair growth and tropism in a randomized clinical trial. Journal of medicinal food, 21(1), 90-103.
Badolati, N., Sommella, E., Riccio, G., Salviati, E., Heintz, D., Bottone, S., ... & Novellino, E. (2018). Annurca apple polyphenols ignite keratin production in hair follicles by inhibiting the pentose phosphate pathway and amino acid oxidation. Nutrients, 10(10), 1406.
Riccio, G., Sommella, E., Badolati, N., Salviati, E., Bottone, S., Campiglia, P., ... & Novellino, E. (2018). Annurca apple polyphenols protect murine hair follicles from taxane induced dystrophy and hijacks polyunsaturated fatty acid metabolism toward β-oxidation. Nutrients, 10(11), 1808.
Piccolo, M., Ferraro, M. G., Maione, F., Maisto, M., Stornaiuolo, M., Tenore, G. C., ... & Novellino, E. (2019). Induction of hair keratins expression by an annurca apple-based nutraceutical formulation in human follicular cells. Nutrients, 11(12), 3041.
Badolati, N., Masselli, R., Maisto, M., Di Minno, A., Tenore, G. C., Stornaiuolo, M., & Novellino, E. (2020). Genotoxicity Assessment of Three Nutraceuticals Containing Natural Antioxidants Extracted from Agri-Food Waste Biomasses. Foods, 9(10), 1461.
Ferraro, M. G., Piccolo, M., Pezzella, A., Guerra, F., Maione, F., Tenore, G. C., ... & Novellino, E. (2021). Promelanogenic effects by an annurca apple-based natural formulation in human primary melanocytes. Clinical, Cosmetic and Investigational Dermatology, 291-301.
Tenore, G. C., Campiglia, P., Ritieni, A., & Novellino, E. (2013). In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca). Food Chemistry, 141(4), 3519-3524.
Tenore, G. C., Caruso, D., Buonomo, G., D'Avino, M., Campiglia, P., Marinelli, L., & Novellino, E. (2017). A healthy balance of plasma cholesterol by a novel annurca apple-based nutraceutical formulation: results of a randomized trial. Journal of medicinal food, 20(3), 288-300.
Sommella, E., Badolati, N., Riccio, G., Salviati, E., Bottone, S., Dentice, M., ... & Novellino, E. (2019). A boost in mitochondrial activity underpins the cholesterol-lowering effect of annurca apple polyphenols on hepatic cells. Nutrients, 11(1), 163.