國際文獻
改善關節炎(疼痛)
(Emy et al., 2016).
This includes:
- 結構蛋白與糖胺聚醣組成特性
- 生物利用度與安全性評估
- 食品加工穩定性與配方相容性
Note: 本內容僅為研究應用方向整理，非效果或結果宣稱
適用族群
適用劑型
膠囊
錠劑
粉包
相關資訊
常見問答
NEM® 是一種從新鮮雞蛋內膜層中，透過獨家專利分離與乾燥技術提取出的營養原料，含有標準化的玻尿酸、軟骨素與膠原蛋白
NEM® 為專利的內膜層萃取，具有標準化的成分定量管控，並有豐富的臨床研究文獻支持其效果，與一般僅將蛋殼磨碎的粉末不同
NEM® 專利蛋殼膜核心指標成分包括玻尿酸、軟骨素以及膠原蛋白，形成標準化的結構基質
根據臨床研究，連續使用 10 天即可開始觀察到關節疼痛與僵硬感的改善
NEM® 是將食品生產過程中的副產物再利用，轉化為高品質營養原料，具有環保與永續循環的價值
NEM® 非常適合運動與戶外活動族群、注重日常營養品質的成年人，以及追求功能性素材的銀髮族
NEM® 通過了 GMP、Halal（清真認證）以及 Kosher（猶太潔食認證），符合嚴格的食品級供應鏈管理
是的，它源自天然雞蛋內膜層，是屬於 Clean Label 的天然營養來源
建議將產品儲存於陰涼乾燥處，並避免暴露在高溫與潮濕的環境中
因為它透過專利技術將食品工業的雞蛋副產物轉化為高價值原料，獲得 Upcycled Certified 認證，符合現代永續發展趨勢
參考文獻
Ruff, K. J., Winkler, A., Jackson, R. W., DeVore, D. P., & Ritz, B. W. (2009). Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Clinical rheumatology, 28(8), 907-914.
Ruff, K. J., DeVore, D. P., Leu, M. D., & Robinson, M. A. (2009). Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. Clinical Interventions in Aging, 235-240.
Benson, K. F., Ruff, K. J., & Jensen, G. S. (2012). Effects of natural eggshell membrane (NEM) on cytokine production in cultures of peripheral blood mononuclear cells: increased suppression of tumor necrosis factor-α levels after in vitro digestion. Journal of Medicinal Food, 15(4), 360-368.
Ruff, K. J., Endres, J. R., Clewell, A. E., Szabo, J. R., & Schauss, A. G. (2012). Safety evaluation of a natural eggshell membrane-derived product. Food and chemical toxicology, 50(3-4), 604-611. Danesch, U., Seybold, M., Rittinghausen, R., Treibel, W., & Bitterlich, N. (2014). NEM® brand eggshell membrane effective in the treatment of pain associated with knee and hip osteoarthritis: Results from a six center, open label German clinical study. J Arthritis, 3(3), 136.
Danesch, U., Seybold, M., Rittinghausen, R., Treibel, W., & Bitterlich, N. (2014). NEM® brand eggshell membrane effective in the treatment of pain associated with knee and hip osteoarthritis: Results from a six center, open label German clinical study. J Arthritis, 3(3), 136.
Ruff, K. J., & DeVore, D. P. (2014). Reduction of pro-inflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membrane-derived product. Mod Res Inflamm, 3(1), 19-25.
Sim, B. Y., Bak, J. W., Jin, H., Jun, J. A., Choi, H. J., Kwon, C. J., ... & Kim, D. H. (2015). Effects of natural eggshell membrane (NEM) on monosodium iodoacetate-induced arthritis in rats. Journal of Nutrition and Health, 48(4), 310-318.
Ruff, K. J., Durham, P. L., O’Reilly, A., & Long, F. D. (2015). Eggshell membrane hydrolyzates activate NF-κB in vitro: possible implications for in vivo efficacy. Journal of inflammation research, 49-57.